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Summary of transcriptome data used in this study

Journal: Journal of Alzheimer's Disease

Article Title: Pathogenomic Signature and Aberrant Neurogenic Events in Experimental Cerebral Ischemic Stroke: A Neurotranscriptomic-Based Implication for Dementia

doi: 10.3233/JAD-220831

Figure Lengend Snippet: Summary of transcriptome data used in this study

Article Snippet: GSE78731 , 5 , 5 , GPL15084 Agilent-028279 SurePrint G3 Rat GE 8x60K Microarray (Probe Name version) , [ ] .

Techniques: Microarray, Expressing

Overview of the enrichment analysis process. Synopsis of a meta-analysis conducted in this study. 10 microarray datasets comprising a total of 97 samples were chosen from the NCBI GEO webpage. Datasets were annotated with Entrez id to facilitate compatibility in network analyst 3.0 software. After validation, the data were uploaded to Network analyst software, where the samples were normalized and subjected to meta-analysis, thus obtaining the resulting ranked differentially expressed gene list comprising 939 genes. The differentially expressed genes between sham and MCAo stroke-affected animals were subjected to enrichment analysis through Cytoscape, WebGestalt and string analysis.

Journal: Journal of Alzheimer's Disease

Article Title: Pathogenomic Signature and Aberrant Neurogenic Events in Experimental Cerebral Ischemic Stroke: A Neurotranscriptomic-Based Implication for Dementia

doi: 10.3233/JAD-220831

Figure Lengend Snippet: Overview of the enrichment analysis process. Synopsis of a meta-analysis conducted in this study. 10 microarray datasets comprising a total of 97 samples were chosen from the NCBI GEO webpage. Datasets were annotated with Entrez id to facilitate compatibility in network analyst 3.0 software. After validation, the data were uploaded to Network analyst software, where the samples were normalized and subjected to meta-analysis, thus obtaining the resulting ranked differentially expressed gene list comprising 939 genes. The differentially expressed genes between sham and MCAo stroke-affected animals were subjected to enrichment analysis through Cytoscape, WebGestalt and string analysis.

Article Snippet: GSE78731 , 5 , 5 , GPL15084 Agilent-028279 SurePrint G3 Rat GE 8x60K Microarray (Probe Name version) , [ ] .

Techniques: Microarray, Software

Normalization of datasets. Normalization of transcriptome data. A) Total intensity distribution among microarray datasets before and after normalization is shown. B) Variation in intensity values from each sample before and after normalization is shown.

Journal: Journal of Alzheimer's Disease

Article Title: Pathogenomic Signature and Aberrant Neurogenic Events in Experimental Cerebral Ischemic Stroke: A Neurotranscriptomic-Based Implication for Dementia

doi: 10.3233/JAD-220831

Figure Lengend Snippet: Normalization of datasets. Normalization of transcriptome data. A) Total intensity distribution among microarray datasets before and after normalization is shown. B) Variation in intensity values from each sample before and after normalization is shown.

Article Snippet: GSE78731 , 5 , 5 , GPL15084 Agilent-028279 SurePrint G3 Rat GE 8x60K Microarray (Probe Name version) , [ ] .

Techniques: Microarray

Detailed information about the datasets.

Journal: Frontiers in Neuroscience

Article Title: Alteration of N 6 -Methyladenosine mRNA Methylation in a Rat Model of Cerebral Ischemia–Reperfusion Injury

doi: 10.3389/fnins.2021.605654

Figure Lengend Snippet: Detailed information about the datasets.

Article Snippet: GSE78731 , GPL15084 , Agilent-028279 SurePrint G3 Rat GE 8x60K Microarray , 5 , 5 , .

Techniques: Microarray